James M Cook Selected Research

Dimenhydrinate (DMH)

1/2021

8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABAA Receptor.

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James M Cook Research Topics

Disease

13	Ataxia (Dyssynergia) 12/2022 - 06/2005
11	Pain (Aches) 04/2024 - 03/2011
10	Seizures (Absence Seizure) 01/2024 - 04/2014
10	Neoplasms (Cancer) 12/2023 - 04/2002
10	Asthma (Bronchial Asthma) 01/2022 - 01/2016
7	Schizophrenia (Dementia Praecox) 01/2023 - 08/2011
6	Alcoholism (Alcohol Abuse) 01/2023 - 12/2003
6	Infections 11/2019 - 03/2009
5	Psychotic Disorders (Schizoaffective Disorder) 02/2024 - 01/2015
5	Epilepsy (Aura) 01/2024 - 10/2018
5	Respiratory Hypersensitivity 02/2022 - 01/2016
5	Inflammation (Inflammations) 01/2022 - 11/2013
4	Neuralgia (Stump Neuralgia) 04/2024 - 03/2011
4	Cognitive Dysfunction 04/2024 - 01/2015
4	Shock 02/2024 - 12/2010
4	Pneumonia (Pneumonitis) 02/2022 - 01/2020
3	Hyperalgesia 04/2024 - 03/2014
3	Autistic Disorder (Autism) 08/2023 - 11/2016
3	Post-Traumatic Epilepsy (Epilepsy, Post Traumatic) 01/2022 - 01/2020
2	Temporal Lobe Epilepsy 01/2024 - 07/2023
2	Tremor (Tremors) 01/2023 - 01/2022
2	Postpartum Depression (Post-Natal Depression) 01/2022 - 01/2022
2	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 12/2020
2	Mental Disorders (Mental Disorder) 01/2022 - 04/2019
2	Chronic Pain 01/2022 - 03/2011
2	Bronchial Spasm 12/2020 - 01/2012
2	Medulloblastoma 05/2019 - 04/2014
2	Sleep Initiation and Maintenance Disorders (Insomnia) 07/2017 - 05/2002
2	Alzheimer Disease (Alzheimer's Disease) 11/2016 - 10/2009
2	Melioidosis 01/2012 - 01/2012
2	Breast Neoplasms (Breast Cancer) 04/2008 - 12/2006
1	Schistosomiasis (Bilharziasis) 01/2024
1	Parasitic Diseases (Parasitic Disease) 01/2024
1	Neglected Diseases 01/2024
1	Adenocarcinoma of Lung 12/2023
1	Lung Neoplasms (Lung Cancer) 12/2023
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2023
1	Brain Neoplasms (Brain Tumor) 12/2023
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2023

Drug/Important Bio-Agent (IBA)

16	gamma-Aminobutyric Acid (GABA)IBA 02/2024 - 12/2003
15	GABA-A Receptors (GABA(A) Receptor)IBA 04/2024 - 05/2002
14	LigandsIBA 01/2023 - 02/2004
13	BenzodiazepinesIBA 01/2024 - 05/2002
10	KRM-II-81IBA 04/2024 - 01/2017
9	Diazepam (Valium)FDA LinkGeneric 12/2022 - 06/2009
8	Dopamine (Intropin)FDA LinkGeneric 02/2024 - 08/2011
8	Aminobutyrates (Aminobutyric Acid)IBA 01/2022 - 01/2015
8	MIDD0301IBA 01/2022 - 01/2018
7	Anticonvulsants (Antiepileptic Drugs)IBA 01/2024 - 11/2013
6	Zolpidem (Ambien)FDA LinkGeneric 01/2023 - 03/2005
5	Pentylenetetrazole (Metrazol)IBA 01/2024 - 05/2014
5	Anti-Anxiety Agents (Anxiolytics)IBA 01/2021 - 12/2010
4	Antipsychotic Agents (Antipsychotics)IBA 07/2023 - 03/2014
4	OvalbuminIBA 12/2020 - 01/2016
4	Hypnotics and Sedatives (Sedatives)IBA 01/2020 - 03/2011
3	SH-053-2'F-R-CH3IBA 08/2023 - 01/2015
3	Methylazoxymethanol AcetateIBA 01/2023 - 08/2011
3	LipopolysaccharidesIBA 02/2022 - 12/2020
3	Midazolam (Versed)FDA LinkGeneric 11/2021 - 03/2005
3	Alprazolam (Xanax)FDA LinkGeneric 11/2021 - 08/2006
3	Anti-Bacterial Agents (Antibiotics)IBA 02/2012 - 01/2012
2	Freund's AdjuvantIBA 04/2024 - 01/2021
2	Flumazenil (Romazicon)FDA LinkGeneric 04/2024 - 04/2012
2	Therapeutic UsesIBA 01/2023 - 01/2016
2	Albuterol (Salbutamol)FDA LinkGeneric 02/2022 - 12/2020
2	SteroidsIBA 02/2022 - 12/2020
2	NeurosteroidsIBA 01/2022 - 01/2022
2	AnionsIBA 01/2021 - 05/2019
2	ChloridesIBA 01/2021 - 05/2019
2	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2021 - 04/2014
2	Methacholine Chloride (Methacholine)FDA Link 12/2020 - 01/2017
2	Small Interfering RNA (siRNA)IBA 01/2019 - 04/2014
2	ZymosanIBA 01/2017 - 03/2011
2	Carbolines (Beta-Carbolines)IBA 11/2015 - 11/2010
2	PS121912IBA 11/2015 - 10/2014
2	Amphetamine (Amfetamine)FDA LinkGeneric 09/2015 - 01/2015
2	Ceftazidime (Fortum)FDA LinkGeneric 01/2012 - 01/2012
2	Mitochondrial DNA (mtDNA)IBA 04/2011 - 03/2009
2	Etoposide (VP 16)FDA LinkGeneric 04/2008 - 04/2002
2	Proteins (Proteins, Gene)FDA Link 04/2008 - 12/2006
1	4- chloro- 3- (6- (5- (2- hydroxypropan- 2- yl)- 1H- 1,3- benzodiazol- 1- yl)pyridin- 2- yl)benzonitrileIBA 04/2024
1	Antiparasitic Agents (Antiparasitics)IBA 01/2024
1	Praziquantel (Biltricide)FDA Link 01/2024
1	meclonazepamIBA 01/2024
1	OxazolesIBA 01/2024
1	Docetaxel (Taxotere)FDA Link 12/2023
1	rat PDCD5 proteinIBA 12/2023
1	Pilocarpine (Ocusert)FDA LinkGeneric 07/2023
1	HarmalineIBA 01/2023
1	Glutamic Acid (Glutamate)FDA Link 01/2023
1	Pimozide (Orap)FDA Link 01/2023
1	Cycloserine (Seromycin)FDA Link 01/2023
1	Tetrabenazine (Nitoman)FDA Link 01/2023
1	Nootropic Agents (Nootropics)IBA 01/2023

Therapy/Procedure

9	Therapeutics 12/2023 - 01/2012
4	Oral Administration 01/2024 - 01/2018
3	Deep Sedation 11/2021 - 01/2018
2	Radiotherapy 12/2023 - 01/2021
2	Self Administration (Administration, Self) 11/2015 - 03/2004
2	Drug Therapy (Chemotherapy) 04/2014 - 01/2012